EXPERIENCE Al Yarmouk Teaching Hospital (Ministry of Health, Baghdad, Iraq, March 2009- March 2010). Pharmacist under training. Management of medicine supply and health equipment to different hospital departments. Work in concert with physicians to administer safe drug therapy regimens. Ministry of health representative to fulfill the hospital needs of medicines from the private sector. Seminar presenting and weekly report of newly admitted cases at the hospital. The University of Baghdad, College of Pharmacy (Ministry of Higher Education and Scientific Research, Baghdad, Iraq, March 2010- August 2018). Laboratory instructor in the clinical pharmacy department (March 2010- March 2011). Teaching students in the final fifth year how to conduct the patient health information. Preparing and managing exams and quizzes in clinical pharmacy courses and ethics. Laboratory instructor in the pharmaceutical chemistry department (March 2011- July 2014). Laboratory and chemicals inventory and design for undergraduate students’ organic and inorganic chemistry experiments in safety protocol procedures. Monitoring students’ progress in performing their experiment independently with the growing ability to identify unknown chemicals by following specific guidelines. Licensed pharmacist (Iraq, 2012-present). Visiting lecturer Al Yarmouk College, Pharmacy Department (Iraq, Baghdad, 2011-2012). Al Israa College, Pharmacy Department (Iraq, Baghdad, Fall 2013). Al Rafedien College, Pharmacy Department (Iraq, Baghdad, 2017-2018). Teaching assistant, The University of Toledo, Toledo, Ohio, Aug 2015-present. MBC 3310 Medicinal Chemistry I: Drug Action and Design (Fall 2015, 2016). MBC 3880 Medicinal and the Biological Chemistry Laboratory (Fall 2019, 2020). MBC 3860 Microbiology for Pharmaceutical Professionals (Spring 2019, 2020, 2021, 2023). MBC 3552 Physiological Chemistry II Cellular Metabolism and Homeostasis (Spring 2021, 2022, 2023). Design the experiments and set up the lab for the active learning synthesis section. Grading of lecture homework. Proctoring midterms and final exams.
PROJECTS Design, Synthesis, and biological evaluation of PF543 Analogs as Two Pore Channel Blockers. More than 100 compounds were synthesized by introducing different steric and electronic chemical groups. Extensive structural-activity relationship studies were collected from the synthesized compounds. The purity standard of the final compound was achieved by complete NMR and mass characterization along with HPLC analysis. Sea urchin egg homogenate was used as a golden standard to evaluate the inhibitory action of PF543 analogs to block NAADP- Calcium mediated release through the two-pore channel. DO.11.10 cells were used as another biological assay to explore the most potent compounds. Off-target activity, such as Sphingosine kinase II inhibition, was also studied using a human sphingosine kinase kit. Synthesis of 2’- Hydroxymethyl Cytidine as a Potential Inhibitor for Hepatitis C Virus Polymerase Enzyme. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1470333250. (Master thesis 2016). 2’-Modified nucleoside was successfully synthesized with complete characterization to work as a chain terminator targeting NS5P HCV polymerase enzyme. Docking program was helped and guided to develop other sets of Sofosbuvir analogs as potent antiviral agents. Repeat with modified synthetic procedures, synthesis of 5’-Pseudouridine radical precursors as a research tool to study the oxidative RNA damages. Developed and design new productive procedures to synthesize the fully protected Pseudouridine on the gram scale starting from protected ribose. Synthesis of cyclic-di-GMP as an essential component in some gram-negative biofilm components.