Pharmacy

Pharmacology &toxicology

• Clinical Biochemistry • Principal biochemistry • Molecular biology • Laboratory Sciences

Medical and pharmaceutical research

Nanotecnology

My research interests focus on the development and modification of structural ceramics (specifically zirconia) using advanced mechanical and biomechanical nanotechnology in dental applications.

Pharmacy

pharmacy pharmaceutics industrial pharmacy drug delivery nanotechnology

Pharmaceutical sciences

Pharmaceutics ,industrial pharmacy and nanotechnology

Veterinary medicine

Pharmaceutical formulation development and drug delivery systems Clinical pharmacy and patient care optimization Drug interactions and adverse drug reactions

Surface and Corrosion Chemistry

PROJECTS Design, Synthesis, and biological evaluation of PF543 Analogs as Two Pore Channel Blockers. More than 100 compounds were synthesized by introducing different steric and electronic chemical groups. Extensive structural-activity relationship studies were collected from the synthesized compounds.  The purity standard of the final compound was achieved by complete NMR and mass characterization along with HPLC analysis. Sea urchin egg homogenate was used as a golden standard to evaluate the inhibitory action of PF543 analogs to block NAADP- Calcium mediated release through the two-pore channel. DO.11.10 cells were used as another biological assay to explore the most potent compounds. Off-target activity, such as Sphingosine kinase II inhibition, was also studied using a human sphingosine kinase kit. Synthesis of 2’- Hydroxymethyl Cytidine as a Potential Inhibitor for Hepatitis C Virus Polymerase Enzyme. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1470333250. (Master thesis 2016). 2’-Modified nucleoside was successfully synthesized with complete characterization to work as a chain terminator targeting NS5P HCV polymerase enzyme. Docking program was helped and guided to develop other sets of Sofosbuvir analogs as potent antiviral agents. Repeat with modified synthetic procedures, synthesis of 5’-Pseudouridine radical precursors as a research tool to study the oxidative RNA damages. Developed and design new productive procedures to synthesize the fully protected Pseudouridine on the gram scale starting from protected ribose. Synthesis of cyclic-di-GMP as an essential component in some gram-negative biofilm components.

Organic synthesis

pharmacology, clinical pharmacology, clinical pharmacy,

Pharmacy sciences and pharmaceutical chemistry

1- Pharmacokinetic parameters of ondansetron in rats after oral solution and transdermal invasomes gel: A comparison study OS Salih, EJ Al-Akkam J Adv Pharm Edu Res 13 (1), 117 2- Characterization and Animal Skin Irritations Investigation of Vemurafenib Microemulsion-Based Hydrogel Using Oily Ionic Liquid MJ Neamah, EJ Al-Akkam The Iraqi Journal of Veterinary Medicine 48 (1), 81-92 3- Extraction, purification and evaluation of prodigiosin from Serratia marcescens for therapeutic potential against urinary tract infections June 2025 · JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA · 28(2):1361 DOI: 10.51470/jez.2025.28.2.1361