الصيدلة

علم الادويه والسموم

# الكيمياء الحياتية السريرية # مبادئ الكيمياء الحيوية # البيولوجيا الجزيئية # علوم المختبرات

بحوث صيدلانية وطبية

البحوث نانوتكنلوجي

اهتمامي البحثي ينصب على تطوير وتعديل السيراميك الإنشائي (خاصة الزركونيا) باستخدام تقنيات النانو لتحسين أدائه الميكانيكي والحيوي في تطبيقات طب الأسنان

الصيدله

صيدلة صيدلانيات صيدلة صناعية توصيل دوائي علم جسيمات النانو

العلوم الصيدلانية

الصيدلانيات الصيدلة الصناعية والتقنيات النانوية

Veterinary medicine

تطوير المستحضرات الصيدلانية وأنظمة توصيل الدواء الصيدلة السريرية وتحسين رعاية المرضى التداخلات الدوائية والآثار الجانبية للأدوية

كيمياء السطح و التأكل

PROJECTS Design, Synthesis, and biological evaluation of PF543 Analogs as Two Pore Channel Blockers. More than 100 compounds were synthesized by introducing different steric and electronic chemical groups. Extensive structural-activity relationship studies were collected from the synthesized compounds.  The purity standard of the final compound was achieved by complete NMR and mass characterization along with HPLC analysis. Sea urchin egg homogenate was used as a golden standard to evaluate the inhibitory action of PF543 analogs to block NAADP- Calcium mediated release through the two-pore channel. DO.11.10 cells were used as another biological assay to explore the most potent compounds. Off-target activity, such as Sphingosine kinase II inhibition, was also studied using a human sphingosine kinase kit. Synthesis of 2’- Hydroxymethyl Cytidine as a Potential Inhibitor for Hepatitis C Virus Polymerase Enzyme. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1470333250. (Master thesis 2016). 2’-Modified nucleoside was successfully synthesized with complete characterization to work as a chain terminator targeting NS5P HCV polymerase enzyme. Docking program was helped and guided to develop other sets of Sofosbuvir analogs as potent antiviral agents. Repeat with modified synthetic procedures, synthesis of 5’-Pseudouridine radical precursors as a research tool to study the oxidative RNA damages. Developed and design new productive procedures to synthesize the fully protected Pseudouridine on the gram scale starting from protected ribose. Synthesis of cyclic-di-GMP as an essential component in some gram-negative biofilm components.

تصنيع المركبات العضويه والمضاده للالتهابات

علم الادوية, علم الادوية السريري, الصيدلة السريرية

علوم الصيدلة والكيمياء الصيدلانية

1- Pharmacokinetic parameters of ondansetron in rats after oral solution and transdermal invasomes gel: A comparison study OS Salih, EJ Al-Akkam J Adv Pharm Edu Res 13 (1), 117 2- Characterization and Animal Skin Irritations Investigation of Vemurafenib Microemulsion-Based Hydrogel Using Oily Ionic Liquid MJ Neamah, EJ Al-Akkam The Iraqi Journal of Veterinary Medicine 48 (1), 81-92 3- Extraction, purification and evaluation of prodigiosin from Serratia marcescens for therapeutic potential against urinary tract infections June 2025 · JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA · 28(2):1361 DOI: 10.51470/jez.2025.28.2.1361